MONDAY JANUARY 27th 2020
- 12:30 Welcome lunch and registration
- 14:00 Official opening
- 14:20 Prof. Matthew Francis – Protein-Protein Coupling Using Enzymatic Oxidative Coupling Reactions
- 15:00 Dr Sébastien Gouin – From the design of an antibacterial glycoconjugate to the development of a chemoselective bioconjugation method for tyrosine.
- 15:20 Dr Elisabetta Mileo – Nitroxide-based spin tags coupled to EPR spectroscopy: investigation of protein structural dynamics in vitro and inside cells
- 15:40 Ruben Tomás – Controlling Synthetic Polymer Ligation to Metabolically Labelled Cellular Interfaces to Introduce Non-native Functionality
- 15:50 Coffee Break + Poster session 1
- 16:30 Dr Vladimir Torbeev – Making order out of disordered proteins
- 17:00 Dr Olivier Sénèque – How chemoselective ligations make the design of peptide-based responsive luminescent probes easier
- 17:30 Dr Somnath Mukherjee – Impact of site-specific non-enzymatic posttranslational modification on the structure-activity attributes of human Heat Shock Protein 27 (Hsp27)
- 17:50 Dr Elisabeth Garanger – Expanding the toolbox of chemoselective modifications of protein-like polymers at methionyl residues
- 18:00 Coffee Break
- 18:30 Public lecture in French: Dr Denis Servent – Venins, du poison au médicament
TUESDAY JANUARY 28th 2020
- 08:45 Welcome coffee
- 09:00 Prof. Lutz Ackermann – C─H Activation as an Transformative Tool for Late-stage Diversification of Biomolecules
- 09:40 Dr Samir Messaoudi – Synthesis of aryl-thioglycopeptides through chemoselective Pd-mediated conjugation
- 10:00 Rebecca Schäfer – The Bioorthogonal Isonitrile-Chlorooxime Ligation
- 10:10 Coffee Break + Poster session 2
- 11:10 Dr Didier Boturyn – Design of RGD peptide conjugates for imaging and therapeutic applications
- 11:50 Prof. Beat Fierz – Synthetic and single-molecule exploration of the dynamic chromatin landscape
- 12:20 Lunch
- 13:30 Dr Frédéric Taran – Recent advances in fast, bioorthogonal ligation reactions
- 14:10 Dr Cyrille Sabot – From organic methodology to the development of chemoselective ligations
- 14:40 Dr Laia Miret Casals – Furan crosslink technology: from in vitro analysis of peptide-protein interactions to GPCR-ligand interactions on live cells
- 15:00 Dr Pierre Milbeo – Development of Novel Thiol-ene Mediated Peptide Ligation Strategies
- 15:20 Dr Gosuke Hayashi – Chemical synthesis of histone proteins through novel ligation strategies
- 15:40 Coffee Break + Poster session 3
- 16:20 Prof. Carlo Unverzagt – Merging Chemistries for the Synthesis and Evaluation of Homogenous Glycoproteins
- 17:00 Dr Kevin Neumann – Cyanosulfurylide as a protecting group for carboxylic acid during peptide synthesis
- 17:20 Prof. Wenshe Liu – Phage-Encoded Noncanonical Amino Acids for Drug Discovery
- 17:40 Guided visit of Orléans town center
WEDNESDAY JANUARY 29th 2020
- 08:45 Welcome coffee
- 09:00 Dr Oleg Melnyk – A cysteine selenosulfide redox switch for protein chemical synthesis
- 09:40 Dr Fabienne Burlina – Extending chemical ligation for the synthesis of proteins: Application to NEMO ubiquitylation
- 10:10 Dr Marina Rubini – Semisynthetic approaches for studying post-translational modifications
- 10:30 Coffee Break
- 11:00 Dr Barbara Bernardim – Title to be announced
- 11:20 Prof. Alexander Dömling – Multicomponent reaction chemistry: From novel small molecules to automated nano chemistry to stapled peptides
- 12:00 Official closing
- 12:10 Farewell cocktail
